| Name: TYRO protein tyrosine kinase binding protein |
| Aliases: DAP12, KARAP, Karap, killer cell activating receptor associated protein |
| Description: PHENOTYPE: Homozygotes for targeted null mutations exhibit osteopetrosis, hypomyelination (especially of the thalamus), synaptic degeneration, and impaired oligodendrocyte, NK, and dendritic cell function. [provided by MGI curators] |
| Crossreferences: MGI:1277211, ENSEMBL:ENSMUSG00000030579, UniProtKB:Q3U419, UniProtKB:A0A140LHP7, UniProtKB:A0A140LI31, NCBI_Gene:22177, UniProtKB:O54885 |
| This information is supplied by the AllianceGenome.org API. |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CLow Blood Monocytes | -0.0935 | 0.252 | 0.89947847561857 |
| Ly6CHigh Brain Monocytes | 0.5243 | 0.2522 | 0.164236304 |
| CCR2High Brain Macrophages | 0.718 | 0.2362 | 0.015661464321211 |
| CCR2Low Brain Macrophages | 0.8202 | 0.2363 | 0.004028035 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 0.0935 | 0.252 | 0.89947847561857 |
| Ly6CHigh Brain Monocytes | 0.6178 | 0.2522 | 0.062702173 |
| CCR2High Brain Macrophages | 0.8115 | 0.2361 | 0.004299156 |
| CCR2Low Brain Macrophages | 0.9137 | 0.2362 | 0.001011041 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | -0.5243 | 0.2522 | 0.164236304 |
| Ly6CLow Blood Monocytes | -0.6178 | 0.2522 | 0.062702173 |
| CCR2High Brain Macrophages | 0.1937 | 0.2364 | 1 |
| CCR2Low Brain Macrophages | 0.2959 | 0.2365 | 0.802304433 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | -0.718 | 0.236 | 0.015661464 |
| Ly6CLow Blood Monocytes | -0.812 | 0.236 | 0.004299156 |
| Ly6CHigh Brain Monocytes | -0.1937 | 0.2364 | 1 |
| CCR2Low Brain Macrophages | 0.1022 | 0.2192 | 1 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | -0.8202 | 0.2363 | 0.004028035 |
| Ly6CLow Blood Monocytes | -0.9137 | 0.2362 | 0.001011041 |
| Ly6CHigh Brain Monocytes | -0.2959 | 0.2365 | 0.802304433 |
| CCR2High Brain Macrophages | -0.1022 | 0.2192 | 1 |