| Name: toll-like receptor 4 |
| Aliases: Lps, RAS-like, family 2, locus 8, Rasl2-8, lipopolysaccharide response |
| Description: PHENOTYPE: Homozygotes for spontaneous or targeted mutations are hyporesponsive to bacterial lipopolysaccharide (LPS) and more susceptible to infection by gram negative bacteria. [provided by MGI curators] |
| Crossreferences: MGI:96824, ENSEMBL:ENSMUSG00000039005, UniProtKB:Q9QUK6, UniProtKB:L0CMZ8, NCBI_Gene:21898, UniProtKB:L0CL36, UniProtKB:A2BHU8, UniProtKB:Q3U4D4, UniProtKB:Q8K2T5 |
| This information is supplied by the AllianceGenome.org API. |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CLow Blood Monocytes | 1.1097 | 0.6256 | 0.26382621385036 |
| Ly6CHigh Brain Monocytes | -0.4582 | 0.6239 | 0.73697169 |
| CCR2High Brain Macrophages | -0.331 | 0.5887 | 0.77109561524895 |
| CCR2Low Brain Macrophages | -0.3729 | 0.5888 | 0.735199255 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | -1.1097 | 0.6256 | 0.26382621385036 |
| Ly6CHigh Brain Monocytes | -1.5679 | 0.6255 | 0.055264315 |
| CCR2High Brain Macrophages | -1.4407 | 0.5903 | 0.057207069 |
| CCR2Low Brain Macrophages | -1.4825 | 0.5905 | 0.047991097 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 0.4582 | 0.6239 | 0.73697169 |
| Ly6CLow Blood Monocytes | 1.5679 | 0.6255 | 0.055264315 |
| CCR2High Brain Macrophages | 0.1272 | 0.5885 | 1 |
| CCR2Low Brain Macrophages | 0.0854 | 0.5887 | 0.998468782 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 0.331 | 0.589 | 0.771095615 |
| Ly6CLow Blood Monocytes | 1.441 | 0.59 | 0.057207069 |
| Ly6CHigh Brain Monocytes | -0.1272 | 0.5885 | 1 |
| CCR2Low Brain Macrophages | -0.0418 | 0.5507 | 1 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 0.3729 | 0.5888 | 0.735199255 |
| Ly6CLow Blood Monocytes | 1.4825 | 0.5905 | 0.047991097 |
| Ly6CHigh Brain Monocytes | -0.0854 | 0.5887 | 0.998468782 |
| CCR2High Brain Macrophages | 0.0418 | 0.5507 | 1 |