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Lair1 - RNA Expression

 

Lair1 - Gene Information

Name: leukocyte-associated Ig-like receptor 1
Aliases: DNA segment, Chr 7, Brigham & Women's Genetics 0421 expressed, Lair-1, mLair-1, D7Bwg0421e, 5133400O11Rik, BB115266, expressed sequence BB115266, RIKEN cDNA 5133400O11 gene
Description: PHENOTYPE: Mice homozygous for a knock-out allele are healthy and of normal longevity but show increased numbers of splenic B, regulatory T, and dendritic cells, and eosinophilia at a young age. Aging homozygotes display a higher frequency of activated and effector/memory T cells and a decreased IgG1 level. [provided by MGI curators]
Crossreferences: MGI:105492, UniProtKB:Q8BG84, ENSEMBL:ENSMUSG00000055541, NCBI_Gene:52855
This information is supplied by the AllianceGenome.org API.
 

Lair1 - Differential Expression

Ly6CHigh Blood Monocytes

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CLow Blood Monocytes -1.598 0.2967 8.3674219189219E-6
Ly6CHigh Brain Monocytes -1.4464 0.2972 2.67E-5
CCR2High Brain Macrophages -2.083 0.2781 4.1121631515757E-12
CCR2Low Brain Macrophages -2.1129 0.2782 1.74E-12

Ly6CLow Blood Monocytes

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes 1.598 0.2967 8.3674219189219E-6
Ly6CHigh Brain Monocytes 0.1516 0.295 0.770731054
CCR2High Brain Macrophages -0.485 0.2757 0.198869061
CCR2Low Brain Macrophages -0.5148 0.2758 0.165171128

Ly6CHigh Brain Monocytes

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes 1.4464 0.2972 2.67E-5
Ly6CLow Blood Monocytes -0.1516 0.295 0.770731054
CCR2High Brain Macrophages -0.6366 0.2764 0.524184304
CCR2Low Brain Macrophages -0.6665 0.2764 0.248213068

CCR2High Brain Macrophages

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes 2.083 0.278 4.11E-12
Ly6CLow Blood Monocytes 0.485 0.276 0.198869061
Ly6CHigh Brain Monocytes 0.6366 0.2764 0.52418430428339
CCR2Low Brain Macrophages -0.0299 0.2557 1

CCR2Low Brain Macrophages

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes 2.1129 0.2782 1.74E-12
Ly6CLow Blood Monocytes 0.5148 0.2758 0.165171128
Ly6CHigh Brain Monocytes 0.6665 0.2764 0.248213068
CCR2High Brain Macrophages 0.0299 0.2557 1