| Name: lymphocyte-activation gene 3 |
| Aliases: Ly66, CD223, lymphocyte antigen 66, LAG-3 |
| Description: PHENOTYPE: Mice homozygous for disruptions in this gene have a generally normal phenotype but do display reduced natural killer cell activity and increased T cell response to infection. [provided by MGI curators] |
| Crossreferences: MGI:106588, UniProtKB:Q61790, ENSEMBL:ENSMUSG00000030124, NCBI_Gene:16768 |
| This information is supplied by the AllianceGenome.org API. |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CLow Blood Monocytes | 0 | 1.0308 | 1 |
| Ly6CHigh Brain Monocytes | -4.5273 | 0.8964 | 1.12E-5 |
| CCR2High Brain Macrophages | -5.2437 | 0.862 | 3.5918423119853E-8 |
| CCR2Low Brain Macrophages | -5.9268 | 0.8605 | 2.28E-10 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 0 | 1.0308 | 1 |
| Ly6CHigh Brain Monocytes | -4.574 | 0.8946 | 7.32E-6 |
| CCR2High Brain Macrophages | -5.2905 | 0.86 | 2.57E-8 |
| CCR2Low Brain Macrophages | -5.9736 | 0.8585 | 1.6E-10 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 4.5273 | 0.8964 | 1.12E-5 |
| Ly6CLow Blood Monocytes | 4.574 | 0.8946 | 7.32E-6 |
| CCR2High Brain Macrophages | -0.7164 | 0.6656 | 1 |
| CCR2Low Brain Macrophages | -1.3996 | 0.6634 | 0.378656605 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 5.244 | 0.862 | 3.59E-8 |
| Ly6CLow Blood Monocytes | 5.29 | 0.86 | 2.57E-8 |
| Ly6CHigh Brain Monocytes | 0.7164 | 0.6656 | 1 |
| CCR2Low Brain Macrophages | -0.6831 | 0.6095 | 1 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 5.9268 | 0.8605 | 2.28E-10 |
| Ly6CLow Blood Monocytes | 5.9736 | 0.8585 | 1.6E-10 |
| Ly6CHigh Brain Monocytes | 1.3996 | 0.6634 | 0.378656605 |
| CCR2High Brain Macrophages | 0.6831 | 0.6095 | 1 |