| Name: Fc receptor, IgG, low affinity IIb |
| Aliases: Fc[g]RII, Fc receptor, IgG, low affinity IIa, expressed sequence AI528646, FcgRII, Fcgr2, LyM-1, Fcr-3, Fcgr2a, Fc-gamma receptor 3, Ly-m20, lymphocyte antigen m20, Lym-1, FcgammaRIIB2, Fc-gamma receptor 2, CD32, FCRII, RIKEN cDNA F630109E10 gene, AI528646, F630109E10Rik, Ly-17, FcgammaRIIB, Fcr-2, Fc receptor, IgG, low affinity II, Fc gamma RIIB, lymphocyte antigen 17 |
| Description: PHENOTYPE: Mutants show increased antibody response, passive cutaneous analphylaxis, autoantibodies and arthritis susceptibility. On C57BL/6, mice die by 9 months with anemia, proteinuria, glomerulonephritis, and inflammatory disease. A strain variant controls expression in germinal center B cells. [provided by MGI curators] |
| Crossreferences: MGI:95499, NCBI_Gene:14130, UniProtKB:E9Q415, UniProtKB:P08101, UniProtKB:A0A0B4J1G1, ENSEMBL:ENSMUSG00000026656, UniProtKB:A0A0B4J1E6 |
| This information is supplied by the AllianceGenome.org API. |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CLow Blood Monocytes | 0.7506 | 0.2552 | 0.036359889586552 |
| Ly6CHigh Brain Monocytes | -1.5748 | 0.2539 | 2.44E-8 |
| CCR2High Brain Macrophages | -1.5543 | 0.2378 | 2.3852043888767E-9 |
| CCR2Low Brain Macrophages | -1.2775 | 0.238 | 1.57E-6 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | -0.7506 | 0.2552 | 0.036359889586552 |
| Ly6CHigh Brain Monocytes | -2.3254 | 0.2545 | 9.17E-18 |
| CCR2High Brain Macrophages | -2.3049 | 0.2384 | 6.03E-20 |
| CCR2Low Brain Macrophages | -2.0281 | 0.2385 | 1.68E-15 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 1.5748 | 0.2539 | 2.44E-8 |
| Ly6CLow Blood Monocytes | 2.3254 | 0.2545 | 9.17E-18 |
| CCR2High Brain Macrophages | 0.0205 | 0.237 | 1 |
| CCR2Low Brain Macrophages | 0.2972 | 0.2372 | 0.802304433 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 1.554 | 0.238 | 2.39E-9 |
| Ly6CLow Blood Monocytes | 2.305 | 0.238 | 6.03E-20 |
| Ly6CHigh Brain Monocytes | -0.0205 | 0.237 | 1 |
| CCR2Low Brain Macrophages | 0.2768 | 0.2198 | 1 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 1.2775 | 0.238 | 1.57E-6 |
| Ly6CLow Blood Monocytes | 2.0281 | 0.2385 | 1.68E-15 |
| Ly6CHigh Brain Monocytes | -0.2972 | 0.2372 | 0.802304433 |
| CCR2High Brain Macrophages | -0.2768 | 0.2198 | 1 |