| Name: CD86 antigen |
| Aliases: B7.2, Cd28l2, lymphocyte antigen 58, CD28 antigen ligand, Ly58, B7-2, Ly-58, MB7-2, B70 |
| Description: PHENOTYPE: Homozygous null mice on an NOD background display a phenotype similar to human Guillain-Barre Syndrome, exhibiting severe peripheral nervous system inflammation, sciatic nerve demyelination, elevated auto-antibodies to myelin protein zero, hindlimb paralysis, and weak forelimb grip. [provided by MGI curators] |
| Crossreferences: MGI:101773, UniProtKB:Q61238, UniProtKB:Q3T9F8, UniProtKB:P42082, NCBI_Gene:12524, UniProtKB:Q3TDR5, ENSEMBL:ENSMUSG00000022901, UniProtKB:Q91YV7, UniProtKB:A0A0X9RAD7, UniProtKB:Q549Q9 |
| This information is supplied by the AllianceGenome.org API. |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CLow Blood Monocytes | 0.367 | 0.3352 | 0.54921780142666 |
| Ly6CHigh Brain Monocytes | -2.5304 | 0.3293 | 1.48E-12 |
| CCR2High Brain Macrophages | -2.4644 | 0.3091 | 1.1547724913327E-13 |
| CCR2Low Brain Macrophages | -2.2531 | 0.3095 | 1.63E-11 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | -0.367 | 0.3352 | 0.54921780142666 |
| Ly6CHigh Brain Monocytes | -2.8975 | 0.33 | 2.06E-16 |
| CCR2High Brain Macrophages | -2.8314 | 0.3098 | 8.06E-18 |
| CCR2Low Brain Macrophages | -2.6201 | 0.3102 | 2.58E-15 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 2.5304 | 0.3293 | 1.48E-12 |
| Ly6CLow Blood Monocytes | 2.8975 | 0.33 | 2.06E-16 |
| CCR2High Brain Macrophages | 0.066 | 0.3035 | 1 |
| CCR2Low Brain Macrophages | 0.2773 | 0.3038 | 0.918498725 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 2.464 | 0.309 | 1.15E-13 |
| Ly6CLow Blood Monocytes | 2.831 | 0.31 | 8.06E-18 |
| Ly6CHigh Brain Monocytes | -0.066 | 0.3035 | 1 |
| CCR2Low Brain Macrophages | 0.2113 | 0.2817 | 1 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 2.2531 | 0.3095 | 1.63E-11 |
| Ly6CLow Blood Monocytes | 2.6201 | 0.3102 | 2.58E-15 |
| Ly6CHigh Brain Monocytes | -0.2773 | 0.3038 | 0.918498725 |
| CCR2High Brain Macrophages | -0.2113 | 0.2817 | 1 |