| Name: CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) |
| Aliases: CLIP, Ii, INVG34, Ia-associated invariant chain |
| Description: PHENOTYPE: Homozygotes for targeted null mutations exhibit impaired transport of MHC class II molecules, poor antigen presentation, and deficiency of CD4+ T cell development and positive selection. [provided by MGI curators] |
| Crossreferences: MGI:96534, UniProtKB:Q545Y5, UniProtKB:Q3U4Q8, ENSEMBL:ENSMUSG00000024610, UniProtKB:P04441, NCBI_Gene:16149 |
| This information is supplied by the AllianceGenome.org API. |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CLow Blood Monocytes | -1.2353 | 0.3948 | 0.023852951243613 |
| Ly6CHigh Brain Monocytes | -1.4252 | 0.3948 | 0.003609595 |
| CCR2High Brain Macrophages | -1.6726 | 0.3706 | 9.4178702318598E-5 |
| CCR2Low Brain Macrophages | -1.5568 | 0.3706 | 0.000301872 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 1.2353 | 0.3948 | 0.023852951243613 |
| Ly6CHigh Brain Monocytes | -0.1899 | 0.3948 | 0.786624852 |
| CCR2High Brain Macrophages | -0.4373 | 0.3706 | 0.421702465 |
| CCR2Low Brain Macrophages | -0.3215 | 0.3706 | 0.572104605 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 1.4252 | 0.3948 | 0.003609595 |
| Ly6CLow Blood Monocytes | 0.1899 | 0.3948 | 0.786624852 |
| CCR2High Brain Macrophages | -0.2474 | 0.3706 | 1 |
| CCR2Low Brain Macrophages | -0.1316 | 0.3706 | 0.989711694 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 1.673 | 0.371 | 9.42E-5 |
| Ly6CLow Blood Monocytes | 0.437 | 0.371 | 0.421702465 |
| Ly6CHigh Brain Monocytes | 0.2474 | 0.3706 | 1 |
| CCR2Low Brain Macrophages | 0.1158 | 0.3445 | 1 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 1.5568 | 0.3706 | 0.000301872 |
| Ly6CLow Blood Monocytes | 0.3215 | 0.3706 | 0.572104605 |
| Ly6CHigh Brain Monocytes | 0.1316 | 0.3706 | 0.989711694 |
| CCR2High Brain Macrophages | -0.1158 | 0.3445 | 1 |