| Name: CD33 molecule |
| Aliases: gp67, Siglec-3 |
| Description: PHENOTYPE: Mice homozygous for disruptions in this gene show slight reductions in mean erythrocyte count and hematocrit and increased concentration of blood aspartate aminotransaminase. There is also a hyporesponsiveness to induced peritonitis and a weaker IL-6 response to LPS-induced systemic inflammation. [provided by MGI curators] |
| Crossreferences: MGI:99440, UniProtKB:A0A0U1RNJ9, ENSEMBL:ENSMUSG00000004609, UniProtKB:Q63994, NCBI_Gene:12489 |
| This information is supplied by the AllianceGenome.org API. |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CLow Blood Monocytes | 2.5804 | 0.489 | 1.4242784568997E-5 |
| Ly6CHigh Brain Monocytes | -0.7451 | 0.4728 | 0.348586173 |
| CCR2High Brain Macrophages | -0.7085 | 0.4439 | 0.2965405063878 |
| CCR2Low Brain Macrophages | -0.7968 | 0.4441 | 0.211031913 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | -2.5804 | 0.489 | 1.4242784568997E-5 |
| Ly6CHigh Brain Monocytes | -3.3255 | 0.4881 | 5.34E-10 |
| CCR2High Brain Macrophages | -3.289 | 0.4603 | 4.92E-11 |
| CCR2Low Brain Macrophages | -3.3773 | 0.4605 | 1.23E-11 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 0.7451 | 0.4728 | 0.348586173 |
| Ly6CLow Blood Monocytes | 3.3255 | 0.4881 | 5.34E-10 |
| CCR2High Brain Macrophages | 0.0365 | 0.4429 | 1 |
| CCR2Low Brain Macrophages | -0.0518 | 0.4431 | 0.998468782 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 0.709 | 0.444 | 0.296540506 |
| Ly6CLow Blood Monocytes | 3.289 | 0.46 | 4.92E-11 |
| Ly6CHigh Brain Monocytes | -0.0365 | 0.4429 | 1 |
| CCR2Low Brain Macrophages | -0.0883 | 0.4119 | 1 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Ly6CHigh Blood Monocytes | 0.7968 | 0.4441 | 0.211031913 |
| Ly6CLow Blood Monocytes | 3.3773 | 0.4605 | 1.23E-11 |
| Ly6CHigh Brain Monocytes | 0.0518 | 0.4431 | 0.998468782 |
| CCR2High Brain Macrophages | 0.0883 | 0.4119 | 1 |